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diff --git a/academic/kraken/README b/academic/kraken/README new file mode 100644 index 0000000000..21eaa3ad87 --- /dev/null +++ b/academic/kraken/README @@ -0,0 +1,21 @@ +Kraken is a system for assigning taxonomic labels to short DNA +sequences, usually obtained through metagenomic studies. Previous +attempts by other bioinformatics software to accomplish this task have +often used sequence alignment or machine learning techniques that were +quite slow, leading to the development of less sensitive but much faster +abundance estimation programs. Kraken aims to achieve high sensitivity +and high speed by utilizing exact alignments of k-mers and a novel +classification algorithm. + +In its fastest mode of operation, for a simulated metagenome of 100 bp +reads, Kraken processed over 4 million reads per minute on a single +core, over 900 times faster than Megablast and over 11 times faster than +the abundance estimation program MetaPhlAn. Kraken's accuracy is +comparable with Megablast, with slightly lower sensitivity and very high +precision. + +REFERENCE +Wood DE, Salzberg SL +Kraken: ultrafast metagenomic sequence classification using exact +alignments. +Genome Biology 2014, 15:R46. |