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+Wise compares a protein sequence to a genomic DNA sequence, allowing for
+introns and frameshifting errors.
+
+The Wise package is now a rather stately bioinformatics package that has
+been around for a while. Its key programs are genewise, a program for
+aligning proteins or protein HMMs to DNA, and dynamite a rather cranky
+"macro language" which automates the production of dynamic programming.