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diff --git a/academic/STAR/README b/academic/STAR/README index 7d410d628f..ae22618ac8 100644 --- a/academic/STAR/README +++ b/academic/STAR/README @@ -2,9 +2,20 @@ STAR aligns short and long RNA-seq reads to a reference genome using uncompressed suffix arrays, resulting in fast, accurate mapping. STAR is capable of unbiased de novo detection of canonical splice junctions, can discover non-canonical splices and chimeric (fusion) -transcripts and can map full-length RNA sequences. Comes with -STARsolo for: mapping, demultiplexing and gene quantification for +transcripts and can map full-length RNA sequences. Comes with +STARsolo for: mapping, demultiplexing and gene quantification for single cell RNA-seq (See STARmanual). +The make command for building the program assumes that the cpu is +supporting AVX extensions, included in intel processors since Sandy +Bridge (2008) and in AMD cpus since Bulldozer (2011). See the +Slackbuild if other processors can be supported. Reference: https://www.ncbi.nlm.nih.gov/pubmed/23104886 + + +LIMITATIONS +This release was tested with the default parameters for human and +mouse genomes. Mammal genomes require at least 16GB of RAM, ideally +32GB. Please contact the author for a list of recommended parameters +for much larger or much smaller genomes. |