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diff --git a/academic/FastTree/README b/academic/FastTree/README new file mode 100644 index 0000000000..4398c4f343 --- /dev/null +++ b/academic/FastTree/README @@ -0,0 +1,17 @@ +FastTree infers approximately-maximum-likelihood phylogenetic trees from +alignments of nucleotide or protein sequences. FastTree can handle +alignments with up to a million of sequences in a reasonable amount of +time and memory. For large alignments, FastTree is 100-1,000 times +faster than PhyML 3.0 or RAxML 7. FastTree is open-source software. + +FastTree is more accurate than PhyML 3 with default settings, and much +more accurate than the distance-matrix methods that are traditionally +used for large alignments. FastTree uses the Jukes-Cantor or generalized +time-reversible (GTR) models of nucleotide evolution and the JTT +(Jones-Taylor-Thornton 1992), WAG (Whelan & Goldman 2001), or LG (Le and +Gascuel 2008) models of amino acid evolution. To account for the varying +rates of evolution across sites, FastTree uses a single rate for each +site (the "CAT" approximation). To quickly estimate the reliability of +each split in the tree, FastTree computes local support values with the +Shimodaira-Hasegawa test (these are the same as PhyML 3's "SH-like local +supports"). |