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diff --git a/academic/iqtree/README b/academic/iqtree/README new file mode 100644 index 0000000000..00f5a25553 --- /dev/null +++ b/academic/iqtree/README @@ -0,0 +1,62 @@ +iqtree (IQ-TREE): Efficient and versatile phylogenomic software by +maximum likelihood (ML) + +The IQ-TREE software was created as the successor of IQPNNI and TREE- +PUZZLE (thus the name IQ-TREE). IQ-TREE was motivated by the rapid +accumulation of phylogenomic data, leading to a need for efficient +phylogenomic software that can handle a large amount of data and provide +more complex models of sequence evolution. To this end, IQ-TREE can +utilize multicore computers and distributed parallel computing to speed +up the analysis. IQ-TREE automatically performs checkpointing to resume +an interrupted analysis. + +As input IQ-TREE accepts all common sequence alignment formats including +PHYLIP, FASTA, Nexus, Clustal and MSF. As output IQ-TREE will write a +self-readable report file (name suffix .iqtree), a NEWICK tree file +(.treefile) which can be visualized by tree viewer programs such as +FigTree, Dendroscope or iTOL. + +Key features +- Efficient search algorithm: Fast and effective stochastic algorithm to + reconstruct phylogenetic trees by maximum likelihood. IQ-TREE compares + favorably to RAxML and PhyML in terms of likelihood while requiring + similar amount of computing time. +- Ultrafast bootstrap: An ultrafast bootstrap approximation (UFBoot) to + assess branch supports. UFBoot is 10 to 40 times faster than RAxML + rapid bootstrap and obtains less biased support values. +- Ultrafast model selection: An ultrafast and automatic model selection + (ModelFinder) which is 10 to 100 times faster than jModelTest and + ProtTest. ModelFinder also finds best-fit partitioning scheme like + PartitionFinder. +- Big Data Analysis: Supporting huge datasets with thousands of + sequences or millions of alignment sites via checkpointing, safe + numerical and low memory mode. Multicore CPUs and parallel MPI system + are utilized to speedup analysis. +- Phylogenetic testing: Several fast branch tests like SH-aLRT and a + Bayes test and tree topology tests like the approximately unbiased + (AU) test. + +The strength of IQ-TREE is the availability of a wide variety of +phylogenetic models: +- Common models: All common substitution models for DNA, protein, codon, + binary and morphological data with rate heterogeneity among sites and + ascertainment bias correction for e.g. SNP data. +- Partition models: Allowing individual models for different genomic + loci (e.g. genes or codon positions), mixed data types, mixed rate + heterogeneity types, linked or unlinked branch lengths between + partitions. +- Mixture models: fully customizable mixture models and empirical + protein mixture models and. +- Polymorphism-aware models: Accounting for incomplete lineage sorting + to infer species tree from genome-wide population data. + +CITING: +To maintain IQ-TREE, support users and secure fundings, it is important +that you cite the papers, whenever the corresponding features were +applied for your analysis. Note that the paper of Nguyen et al. (2015) +only described the tree search algorithm. Thus, it is not enough to only +cite this paper if you, for example, use partition models, where +Chernomor et al. (2016) should be cited. + +Check the "References" file in the package doc folder, as well as, the +program's web-page. |