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diff --git a/academic/WEVOTE/README b/academic/WEVOTE/README new file mode 100644 index 0000000000..7146dcbd2b --- /dev/null +++ b/academic/WEVOTE/README @@ -0,0 +1,26 @@ +WEVOTE (WEighted VOting Taxonomic idEntification) + +WEVOTE is a method that classifies metagenome shotgun sequencing DNA +reads based on an ensemble of existing methods using k-mer based, +marker-based, and naive-similarity based approaches. The performance +evaluation based on fourteen simulated microbiome datasets +consistently demonstrates that WEVOTE achieves a high level of +sensitivity and precision compared to the individual methods across +different taxonomic levels. The major advantage of the WEVOTE pipeline +is that the user can make the choice of which tools to use in order to +explore the trade-off between sensitivity, precision, time and memory. + +The WEVOTE architecture is flexible so that additional taxonomic tools +can be easily added, or the current tools can be replaced by improved +ones. Moreover, the score assigned to the taxon for each read +indicates the confidence level of the assignment. This information is +especially useful for the assessment of false positive annotations at +a particular taxonomic level. The classification score given by WEVOTE +can be used for any downstream analysis that requires the high +confidence of the annotated sequences. + +Publication: +Ahmed A. Metwally, Yang Dai, Patricia W. Finn, and David L. Perkins. +WEVOTE: Weighted Voting Taxonomic Identification Method of Microbial +Sequences. +PloS ONE, 2016. |